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N,N-Dimethylglycine or DMG is a natural substance found in low levels in the body and in certain foods like meat (liver), beans, seeds, and grains. DMG is not found in high levels in your body because it is an intermediary metabolite, meaning it has a temporary role in the cell cycle before it is rapidly broken down into other substances that your body needs. The human body can produce small amounts of DMG from choline and betaine, but supplementation with DMG can result in many health benefits to the body.
DMG (N,N-Dimethylglycine) is the simplest amino acid, glycine whose two hydrogen atoms that have been replaced with methyl (CH3) groups on its nitrogen atom. Research shows it to be physiologically active and important to cell metabolism. DMG supplies essential methyl groups for modification, building, and detoxifying many components in the body.
DMG (N,N-Dimethylglycine) is a metabolic enhancer that can provide increased benefits when supplemented even if there isn’t a deficiency.
DMG makes the process of metabolism (breaking down or building up of compounds in the body) quicker and more efficient.
DMG is a completely safe hypoallergenic nutrient.
We don’t produce as much DMG as we grow older or if we are immune compromised, which leaves us more susceptible to stress and infection.
DMG improves oxygen utilization, detoxification, cell protection, immune system modulation, and enhances the healing.
Extensive research with animals and in clinical testing shows that DMG is an adaptogen that helps maintain homeostasis. Adaptogens like DMG normalize physiological functions and help maintain homeostasis within the body. These physiological functions include blood glucose levels, pH, blood pressure, hypoxic or low oxygen conditions, hormone levels, cholesterol levels, and levels of important biologically active nutrients. DMG has received a great deal of attention because it is beneficial in so many areas of human health and well being. Research and clinical studies over the last 25 years demonstrate that DMG can help the body overcome a number of specific health problems. Since DMG is cost effective and results are usually seen fairly quickly, it should be relatively easy to determine if DMG is for you!
There are many reasons why DMG is important for you:
Cardiovascular Disease -
Decreases elevated triglyceride and cholesterol levels. Improves circulation, helps the body adapt to stress, decreases homocysteine levels, increases glutathione and SAMe.
Cancer -
DMG has anti-tumor properties, modulates the immune system, and helps protect DNA.
Diabetes -
DMG regulates sugar metabolism, helps production of hormones like insulin, helps with cataract prevention, and acts as an antioxidant.
Immune System -
Enhances the immune system by acting as an anti-viral, anti-bacterial, and anti-fungal agent.
Athletic Performance -
Increases oxygen utilization, decreases lactic acid formation, and makes energy production more efficient.
Autism -
DMG acts as a methyl donor, adaptogen, as well as impacting the immune response, and enhancing neurotransmitter production.
Alcoholism/Drug Addictions -
DMG eliminates craving for drugs and alcohol, as well as helping to detoxify the liver.
Neurological Disorders -
DMG reduces seizures frequency and strength, increases circulation, provides building blocks to important neurotransmitters and hormones, and makes energy production more efficient.
Respiratory problems -
DMG increases circulation, increases oxygen utilization, decreases lactic acid, and acts as an adaptogen.
Liver and Kidney Disorders -
DMG acts as a methyl donor, it enhances circulation, enhances glutathione and SAMe producrtion, and has lipotropic properties.
Stress -
DMG acts as an adaptogen and helps the body cope with physical, emotional and metabolic stress, acts as an antioxidant, provides building blocks, increases oxygen utilization, decreases lactic acid, and helps modulate the immune system.
Autoimmune Diseases (like Lupus) -
DMG modulates the immune response in those with autoimmune diseases.
Cataract Prevention –
DMG’s increases circulation, rids the area of optical debris, enhances oxygen utilization at a cellular level, and acts as an antioxidant.
Chronic Fatigue Syndrome/Fibromyalgia -
DMG enhances oxygen utilization, improves circulation, makes energy production more efficient, modulates the immune system, and decreases lactic acid levels.
Degenerative Diseases/Arthritis -
DMG has anti-inflammatory properties and supports the immune system.
General health/Premature Aging -
DMG modulates the immune system, increases circulation, improves oxygen utilization, and acts as an adaptogen and provides building blocks needed for synthesis of important body constituents. Research also suggest that DMG is beneficial in the healing of skin disorders, circulatory insufficiencies, epilepsy, migraines, tension headaches, vascular headaches, autoimmune diseases, asthma, and allergies.
Recommended Ranges for Use of DMG to be taken daily in divided doses:
General Use & Anti-Aging 125-500 mg
Sports Practice & Fitness 375-1,000 mg
Endurance Sports 1,000-2,500 mg
Immune Response (Prevention) 375-750 mg
Compromised Immune Response 750-1,200 mg
Cardiovascular & Circulatory Problems 375-1,000 mg
Diabetics & Hypoglycemics 375-1,000 mg
Autism, ADD, & Seizures 375-1,000 mg
Autoimmune Diseases (Lupus) 750-1,000 mg
Chronic Fatigue, Fibromyalgia 1,000-1,500 mg
Liver Detoxification 750-1,000 mg
Respiratory Dysfunction (Asthma/Allergies) 750-1,000 mg
Stress 250-750 mg
Dear Dr. Kendall, I have a four year son diagnosed with moderate Autism, we have tried numerous options over the past two years in treating his autism with various nutritional supplements, diets, therapies, etc. I had come across information regarding DMG and decided to give it a try,not knowing the proper doasge amount for a child with Autism, I started giving him on 125mg daily in which I did see some direct eye contact establish but nothing signifigant and was told by a medical professional to try TMG that I should see much better results. In doing so my son became very hyperactive and fleeting, I stopped TMG due to the adverse effect. I then decided to place him back on DMG but at a much higher dosage after coming across your recommended dosing for individuals with Autism. He currently is taking 900mg a day in divided doses and has made remarkable progress over the past three months since reintroducing DMG into his daily routine. My son has been non-verbal since nineteen months of age, when he lost the fifteen words he had in his vocabulary as well as all of the developmental milestones he accomplished, after recieving his last series of childhood vaccinations, but thanks to DMG he is now experiencing once again expressive language, direct eye contact,improved motor skills both fine and gross motor. DMG has played a key role in my son's ability to communicate and function on daily basis, thank you for helping him regain some of his abilities to lead a better way of life.
Sincerley,
Laurey Tedeschi
Reply by Dr Kendall
For years DMG has been recommended for those with autism by Dr Bernard Rimland of the Autism Research Institute. Please check out his website at www.autism.com or check out Building Wellness with DMG chapter 7 for more information. Keep us posted!
Dear Dr. Kendall, For the past 6 weeks, I have had a sciatia condition on the right side of my leg. The pain started at my hip and went all the way down to my toes. Getting out of bed in the morning was the worse. Excercising and even walking up stairs was becoming difficult and caused me to limp. As this was my first bout with pain of this degree,I was unsure how to treat it. After reading Building Wellness with DMG, I began taking 1000 mg of DMG daily and within 3 days, the pain was totally gone! I can now move freely and have gone back to sit-ups before my workouts as this was impossible without the DMG! This book could not have come out at a better time. Thank you!
J Fox DC and J Fox DC
Gulfport, MS
Over the years, we've had the opportunity to work with DMG on many types of patients. I work with a lot of cancer patients on chemotherapy and because this drastically suppresses thier immune system, we can keep their immune system functional and they can continue and finish thier chemotherapy treatment. I've seen great results in almost every category of patients we've recommended DMG for with several different types of autoimmune disorders.
Reply by Dr Kendall
DMG has been studied extensively and is shown to have anti-tumor properties. Research shows that DMG's modulates the immune system of those with SLE an autoimmune disease to reduce symptoms associated with autoimmune disorders.
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