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Red Raspberry Ellagic Acid

Daily consumption of 150 grams of red raspberries causes the appearance of circulating levels of ellagic acid
in the blood one hour after administration. Daily administration of our Red Raspberries Ellagic Acid tablets
equals to 22 milligrams or more of pure ellagitannin which is then converted into ellagic acid.

In their book, Complementary and Alternative Cancer Methods Handbook, the American Cancer Society
also indicated that ellagic acid, quote, "prevents the binding of carcinogens to DNA and strengthens
connective tissue, which may keep cancer cells from spreading." Additionally, The American Cancer
Society wrote that ellagic acid may, "reduce heart disease, birth defects, and liver fibrosis and promote
wound healing." They also pointed out that studies demonstrated ellagic acid inhibited tumor growth
and protected against chromosome damage from radiation therapy.(1)

According to Florida State University studies ellagic acid acts as a scavenger to "bind" or chemically
engage cancer-causing chemicals, making them inactive. In addition, Ellagic Acid prevents the binding
of carcinogens to DNA and reduces the incidence of cancer in cultured human cells exposed to carcinogens.

The Ohio State University Extension article, "Evaluation of Ellagic Acid Content of Ohio Berries - Final
Report," concluded that Ellagic acid exhibits anticarcinogenic and antimutagenic activity in humans.
Medical research has shown reductions in the size and number of cancerous tumors when mice are
fed a diet of freeze dried strawberries or raspberries.

References

(1) American Cancer Society's Guide to Complementary and Alternative Cancer Methods. American Cancer Society 2002. p. 203.

Ohio State University Extension References

Bash, W.D., S.J. Schwartz and R.C. Funt. 1996. Small fruit evaluation for ellagic acid content. Proc. Ohio Fruit and Veg. Growers Congress and Roadside Marketing Conference. p. 126-129.

Daniel, E.M., A.S. Krupnick, Y. Hew, J.A. Blinzler, R.M. Nems and G.D. Stoner. 1990. Extraction, stability, and quanlitation of ellagic acid in various fruits and nuts. J. of Food Composition and Analysis 2, p. 338-349.

Funt, R.C., W.D. Bash, S.J. Schwartz, J. Collier and G. Wenneker. 1997. Small fruit cultivar characteristics for ellagic acid and neutracuetical development. Proc. Ohio Fruit and Veg. Growers Congress and Roadside Marketing Conference. p. 110-113.

Funt, R.C., W.D. Bash, S.J. Schwartz, C. Moxley and T.E. Wall. 1998. Evaluation of year to year variation in berries for ellagic acid content and neutracuetical development. Proc. Fruit, Vegetable, Roadside Marketing and Ohio Wine Producers Conf. p. 14-18.

Harris, G.K., G.D. Stoner and S.J. Schwartz. 2000. Effects of freeze dried black raspberries on ayoxymethane induced colon tumors in the F344 rat. OARDC poster session (unpublished).

Jones, K.C. and J.A. Klocke. 1987. Aphid feeding deterrence of ellagitannins, their phenolic hydrolysis products and related phenolic derivatives. Entomol. Expt. Appl. 44:229-234.

Klocke, J.A., B. VanWagenam, and M.F. Bolundrin. 1986. The ellagitannin geranium and its hydrolysis products isolated as insect growth inhibitors from semi-arid land plants. Phytochemistry 25:85-91.

Maas, J.L., S.Y. Wang., G.J. Galletta. 1991a. Evaluation of strawberry genotypes for ellagic acid, an antimutagenic and anticarcinogenic plant phenol. In: The Strawberry Into the 21st Century, A. Dale and J.J. Luby, editors. Timber Press. p. 115-117.

Maas, J.L., G.J. Galletta and G.D. Stoner. 1991b. Ellagic acid, an anticarcinogen in fruits, especially in strawberries. A review. HortScience 26(1)10-14.

Maas, J.L., S.Y. Wang, and G.J. Galletta. 1991c. Evaluation of strawberry cultivars for ellagic acid content. HortScience 26(1)66-68.

SAS Institute. 1990. SAS/STAT User's Guide. 4th Ed. Vol. 2. SAS Institute, Inc. Cary, NC.

Stoner, G.D. and H. Mukhtar. 1995. Polyphenols as cancer chemo-preventive agents. J. of Cellular Biochemistry, Supplement 22:169-180.

What is ellagic acid and how does it work?   

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American Cancer Society Findings

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